A 45-year-old woman comes to her physician with complaints of excessive fatigue and weakness. She says that these symptoms have been present for the past month. On further questioning, she admits having lost 3 kilograms in the last 2 weeks. On physical examination, she is a tired-appearing thin woman. Hyperpigmentation is present over many areas of her body, most prominently over the face, neck and back of hands (areas exposed to light). Increased production of which of the following hormones is the most likely cause of hyperpigmentation in this patient?

Питання КРОК 1 (медицина) · тест з варіантами та поясненням · Medus

EN: A 45-year-old woman comes to her physician with complaints of excessive fatigue and weakness. She says that these symptoms have been present for the past month. On further questioning, she admits having lost 3 kilograms in the last 2 weeks. On physical examination, she is a tired-appearing thin woman. Hyperpigmentation is present over many areas of her body, most prominently over the face, neck and back of hands (areas exposed to light). Increased production of which of the following hormones is the most likely cause of hyperpigmentation in this patient?

Варіанти відповідей

1. Gonadotropins
2. Growth hormone (GII)
3. B-Lipotropin
4. Melanocytc-stimulating hormone (MSH)
5. Thyroid-stimulaiing hormone (TSII)

Answer options (EN)

1. Gonadotropins
2. Growth hormone (GH)
3. β-Lipotropin
4. Melanocyte-stimulating hormone (MSH)
5. Thyroid-stimulating hormone (TSH)

Правильна відповідь

Melanocytc-stimulating hormone (MSH)

EN: Melanocyte-stimulating hormone (MSH)

Пояснення

Гіперпігментація на відкритих ділянках, слабкість, схуднення нагадують первинну недостатність надниркових залоз (хвороба Аддісона). Підвищена секреція АКТГ та MSH (спільний попередник з АКТГ) призводить до потемніння шкіри. ТСГ та інші гормони не дають такої картини.

Зустрічається в буклетах

• 2019 рік (English)

Усі буклети КРОК 1 · Підготовка до КРОК